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KMID : 1151920210030040167
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Chronobiology in Medicine
2021 Volume.3 No. 4 p.167 ~ p.170
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Undiagnosed Obstructive Sleep Apnea and Acute COVID-19 InfectionㅡA Case Series
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Kang Hyeon-Hui
Kim Jin-Hyoung
Kang Byung-Ju
Lee Tae-Hoon
Ra Seung-Won
Seo Kwang-Won
Jegal Yang-Jin
Ahn Jong-Joon
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Abstract
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A recently published study on coronavirus disease 2019 (COVID-19) and obstructive sleep apnea (OSA) suggested that there might be an association between certain risk factors and comorbidities associated with OSA, which are also associated with poor COVID-19 outcomes. However, it is unclear whether undiagnosed OSA correlates with COVID-19 severity in a South Korean population. We identified 7 patients who presented with nocturnal hypoxemia during hospitalization due to COVID-19. All patients underwent polysomnography 5?9 weeks after the infection. We retrospectively collected the patients’ baseline characteristics, hospital admission data, and polysomnography findings. Of the 7 patients, all were diagnosed with OSA after COVID-19 infection. Their mean (±SD) age was 45.4±16.3 years, 57.1% were men, and their mean (±SD) body mass index was 33.4±6.0 kg/m2. Six patients presented with COVID-19-related pneumonia on chest X-rays, 3 of whom were admitted to the intensive care unit during the acute phase. The overnight polysomnography showed a mean AHI of 59.0±38.5/h and an oxygen desaturation index of 57.6±39.7/h. Undiagnosed OSA is a prevalent condition associated with moderate to severe COVID-19 infection. The study patients with sleep apnea and COVID-19 had obesity and severe oxygen desaturation but did not complain of daytime sleepiness.
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KEYWORD
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COVID-19, Sleep apnea, Polysomnography
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